UBE2B, aa1-152, Recombinant, Human (HHR6B, HR6B, RAD6B, RAD6 Homolog B, Ubiquitin Carrier Protein B, Ubiquitin-conjugating Enzyme E2-17kD, Ubiquitin-protein Ligase B)
Biozol Catalog Number:
USB-U0879-89
Supplier Catalog Number:
U0879-89
Alternative Catalog Number:
USB-U0879-89-50
Manufacturer:
US Biological
Category:
Molekularbiologie
UBE2B, also known as ubiquitin-conjugating enzyme E2 B, belongs to E2 ubiquitin-conjugating enzyme family. This protein catalyzes the covalent attachment of ubiquitin to other proteins, and associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on Lys-164. It is required for postreplication repair of UV-damaged DNA. It may be involved in neurite outgrowth. Recombinant protein corresponding to aa1-152 of human UBE2B with a 6x His tag expressed in E.coli. Accession: NP_003328. AA Sequences: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSTP ARRRLMRDFK RLQEDPPVGV SGAPSENNIM QWNAVIFGPE GTPFEDGTFK LVIEFSEEYP NKPPTVRFLS KMFHPNVYAD SICLDILQN RWSPTYDVSS ILTSIQSLLD EPNPNSPANS QAAQLYQENK REYEKRVSAI VEQSWNDS Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
