Ubc9, Recombinant, Human (Ubiquitin Conjugating Enzyme 9)
Catalog Number:
USB-U0880-05
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| Article Name: | Ubc9, Recombinant, Human (Ubiquitin Conjugating Enzyme 9) |
| Biozol Catalog Number: | USB-U0880-05 |
| Supplier Catalog Number: | U0880-05 |
| Alternative Catalog Number: | USB-U0880-05-500 |
| Manufacturer: | US Biological |
| Category: | Molekularbiologie |
| Human Ubc9 is homologous to ubiquitin-conjugating enzymes (E2s). However, instead of conjugating ubiquitin, it conjugates a ubiquitin homologue, small ubiquitin-like modifier 1 (SUMO-1). And hUbc9 retains striking structural and functional conservation with yeast Ubc9. The ubiquitin-dependent protein degradation system has been recognized as a complete enzymatic pathway that is responsible for the selective degradation of abnormal and short-lived proteins. The conjugation of ubiquitin requires the activities of ubiquitin-activating (E1) and -conjugating (E2) enzymes. Molecular Weight: 18kD (158 amino acids) Sequence: MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG TPWEGGLFKL RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED KDWRPAITIK QILLGIQELL NEPNIQDPAQ AEAYTIYCQN RVEYEKRVRA QAKKFAPSS Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Storage and Stability: May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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