Recombinant protein derived from an internal region of human Ubiquilin.
Ubiquilin is a recently discovered protein that is involved in early onset Alzheimers disease. Ubiquilin binds to and promotes aggregation of presenilin proteins. Although the Ubiquilin protein contains ubiquitin-like domains, Ubiquilin appears to increase presenilin synthesis, rather than affect presenilin turnover. Ubiquilin is found in neuropathological lesions that are characteristic of Alzheimers and Parkinsons diseases. Applications: Suitable for use in Immunoprecipitation, ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality:
Monoclonal
Clone Designation:
[6A211]
Purity:
Purified by Protein A affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
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