Recombinant protein derived from an internal region of human Ubiquilin
Ubiquilin is a recently discovered protein that is involved in early onset Alzheimers disease. Ubiquilin binds to and promotes aggregation of presenilin proteins. Although the Ubiquilin protein contains ubiquitin-like domains, Ubiquilin appears to increase presenilin synthesis, rather than affect presenilin turnover. Ubiquilin is found in neuropathological lesions that are characteristic of Alzheimers and Parkinsons diseases. Applications: Suitable for use in Immunoprecipitation, FLISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Clonality:
Monoclonal
Clone Designation:
[6A211]
Purity:
Purified by Protein A affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Fluorescein isothiocyanate (FITC).
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