Vaccinia virus (VACV or VV) is a large, complex enveloped virus belonging to the poxvirus family of viruses. It has a linear double-stranded DNA genome, which is approximately 190kb in length and encodes for approximately 250 genes. The dimensions of the virion are roughly 360 * 270 * 250nm. Vaccinia virus is well-known for its role as a vaccine that eradicated the smallpox disease from our world, making it the first human disease to be successfully eradicated by mankind. This endeavor was carried out by the World Health Organization under the Smallpox Eradication Program. Post eradication of smallpox, scientists have been studying vaccinia virus to use as a tool for delivering genes into biological tissues (gene therapy and genetic engineering). Moreover, due to recent concerns about smallpox resurfacing as a possible agent for bioterrorism, scientists have renewed their interests in studying vaccinia virus. Applications: Suitable for use in Immunofluorescence, ELISA, Immunocytochemistry and Lateral Flow. Other applications not tested. Recommended Dilutions: Immunofluorescence: 1:10-1:50 ELISA: 1:20-1:200 Optimal dilutions to be determined by the researcher. Matched Pair: Capure: 227233 Detection: V0500-13 Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality:
Monoclonal
Clone Designation:
[5E450]
Isotype:
IgG2b
Purity:
Purified by Protein A affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. No stabilizing proteins have been added.
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