VAMP B, aa1-222, Recombinant Human (Vesicle-associated Membrane Protein-associated Protein B, VAMP-B, VAP B, VAPB, VAP-B, ALS8, D2Abb2e, Vamp33b, VAMP C, VAMP-C, VAP C, VAP-C, Vesicle Associated Membrane Protein Associated Protein
Biozol Catalog Number:
USB-V2024-15D
Supplier Catalog Number:
V2024-15D
Alternative Catalog Number:
USB-V2024-15D-100
Manufacturer:
US Biological
Category:
Molekularbiologie
VAPB, also known as vesicle-associated membrane protein (VAMP)-associated protein B, is a type IV transmembrane protein and member of the VAP family of proteins. This protein may play a role in vesicle trafficking. It is found in plasma and intracellular vesicle membranes as a homodimer and heterodimer with VAPA, and interacts with VAMP1 and VAMP2. Defects in VAPB are a cause of amyotrophic lateral sclerosis type 8 and spinal muscular atrophy autosomal dominant Finkel type. Source: Recombinant corresponding to aa1-222 of human recombinant VAPB protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAKVEQVLSL EPQHELKFRG PFTDVVTTNL KLGNPTDRNV CFKVKTTAPR RYCVRPNSGI IDAGASINVS VMLQPFDYDP NEKSKHKFMV QSMFAPTDTS DMEAVWKEAK PEDLMDSKLR CVFELPAEND KPHDVEINKI ISTTASKTET PIVSKSLSSS LDDTEVKKVM EECKRLQGEV QRLREENKQF KEEDGLRMRK TVQSNSPISA LAPTGKEEGL ST Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
