VEGF (Vascular Endothelial Growth Factor, Vascular Permeability Factor, VEGFA, VPF) (APC), IgG1, Clone: [CH-10], Mouse, Monoclonal
Catalog Number:
USB-V2110-11B-APC
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| Article Name: | VEGF (Vascular Endothelial Growth Factor, Vascular Permeability Factor, VEGFA, VPF) (APC), IgG1, Clone: [CH-10], Mouse, Monoclonal |
| Biozol Catalog Number: | USB-V2110-11B-APC |
| Supplier Catalog Number: | V2110-11B-APC |
| Alternative Catalog Number: | USB-V2110-11B-APC-100 |
| Manufacturer: | US Biological |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | WB |
| Immunogen: | Recombinant protein corresponding to mouse VEGF. |
| VEGF (Vascular endothelial growth factor, VEGFA, VEGF-A), a dimeric ligand, is among the most potent angiogenic mitogens. VEGF is secreted by tumor cells and other cells exposed to hypoxia. VEGF is a highly specific mitogen for vascular endothelial cells. Seven VEGF isoforms (a, b, c, d, e, f, g) are generated as a result of alternative splicing from a single VEGF gene. All seven isoforms differ in their molecular mass and in biological properties such as their ability to bind to cell-surface heparan-sulfate proteoglycans. The expression of VEGF is potentiated and is secreted by tumor cells in response to hypoxia, by activated oncogenes, and by a variety of cytokines. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Jurkat cell lysate. Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody. |
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