Vaspin, Recombinant, Human, aa21-414, His-Tag (Visceral Adipose-Specific SERPIN, SERPINA12, Serine proteinase inhibitor-clade A12)

Catalog Number: USB-V2118-10
Article Name: Vaspin, Recombinant, Human, aa21-414, His-Tag (Visceral Adipose-Specific SERPIN, SERPINA12, Serine proteinase inhibitor-clade A12)
Biozol Catalog Number: USB-V2118-10
Supplier Catalog Number: V2118-10
Alternative Catalog Number: USB-V2118-10-100
Manufacturer: US Biological
Category: Molekularbiologie
Vaspin (Visceral adipose-specific SERPIN), a newly identified adipokine, which is a member of serine protease inhibitor family. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that induction of human vaspin mRNA expression in adipose tissue is regulated in a fat depot-specific manner and couil be associated with parameters of obesity, insulin resistance, and glucose metabolism. Recombinant protein corresponding to aa21-414 from human Vaspin fused to His-Tag at N-terminus, expressed in E. coli. Molecular Weight: ~47kD (415 amino acids) AA Sequence: MGSSHHHHHH SSGLVPRGSH MLKPSFSPRN YKALSEVQGW KQRMAAKELA RQNMDLGFKL LKKLAFYNPG RNIFLSPLSI STAFSMLCLG AQDSTLDEIK QGFNFRKMPE KDLHEGFHYI IHELTQKTQD LKLSIGNTLF IDQRLQPQRK FLEDAKNFYS AETILTNFQN LEMAQKQIND FISQKTHGKI NNLIENIDPG TVMLLANYIF FRARWKHEFD PNVTKEEDFF LEKNSSVKVP MMFRSGIYQV GYDDKLSCTI LEIPYQKNIT AIFILPDEGK LKHLEKGLQV DTFSRWKTLL SRRVVDVSVP RLHMTGTFDL KKTLSYIGVS KIFEEHGDLT KIAPHRSLKV GEAVHKAELK MDERGTEGAA GTGAQTLPME TPLVVKIDKP YLLLIYSEKI PSVLFLGKIV NPIGK Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight: 47
NCBI: 776249
UniProt: Q8IW75
Purity: 90% by SDS-PAGE. Purified by using conventional chromatography techniques. Endotoxin: <1EU/1ug (LAL)
Form: Supplied as a liquid in 20mM Tris, pH 8.0, 0.2mM PMSF, 10% glycerol