VSIG1 (V-set and Ig Domain-containing Protein 1, Glycoprotein 34, Cell Surface Antigen 33) (Biotin), Goat
Biozol Catalog Number:
USB-V4965-24
Supplier Catalog Number:
V4965-24
Alternative Catalog Number:
USB-V4965-24-50
Manufacturer:
US Biological
Host:
Goat
Category:
Antikörper
Application:
WB
Immunogen:
Recombinant protein corresponding to Val23-Glu234 from extracellular domain of mouse VSIG1, expressed in NS0 cells. Species Sequence Homology: rat, 94%, human, 81%
VSIG1 (V-set and Ig domain-containing protein 1, also Glycoprotein 34 and Cell surface antigen 33) is a 55-70kD member of the JAM family of Ig-Superfamily proteins. It shows expression on gastric epithelium and testicular germ cells and likely participates in cell adhesion. Mouse VSIG1 precursor is 407 amino acids in length. It is a type I transmembrane glycoprotein that contains a 211aa extracellular domain (ECD) (aa23-234) and a 152aa cytoplasmic region. The ECD contains one V-type (aa23-134) and one C2-type Ig-like domain (aa145-229). Over aa23-234, mouse VSIG1 is 94% and 81% aa identical to rat and human VSIG1, respectively. There is one potential alternate start site at Met108. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 0.1ug/ml detects VSIG1 in recombinant mouse and rat VSIG1 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
