NIK Adenovirus (Ad-CMV-NIK)
Catalog Number:
VBL-1180
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| Article Name: | NIK Adenovirus (Ad-CMV-NIK) |
| Biozol Catalog Number: | VBL-1180 |
| Supplier Catalog Number: | 1180 |
| Alternative Catalog Number: | VBL-1180 |
| Manufacturer: | Vector Biolabs |
| Category: | Sonstiges |
| Alternative Names: | NIK Adenovirus |
| NFiB-Inducing Kinase (NIK) The NFiB transcription factor can be activated by several cytokines including TNF and IL-1. The TNF receptor activates NFiB through the Traf2 adapter protein , whereas the IL-1 receptor activates NFiB in a pathway involving Traf6 . Both Traf2 and Traf6 have been shown to interact with a serine/threonine kinase designated NFkB inducing kinase (NIK), which appears to participate in the NFiB signaling cascades triggered by both TNF and IL-1. NIK associates with, and is a costimulator for IkB kinase i (IKKi). IKKi , in turn, phosphorylates IiB, resulting in I i B degradation and NF i B activation. NIK has sequence similarity to several kinases that participate in MAP kinase cascades. |
| Concentration: | 1x10 10 PFU/ml |
| Buffer: | DMEM, 2% BSA, 2.5% Glycerol |
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