APC Adenovirus (Ad-CBR)

Product Overview

• Article Name: APC Adenovirus (Ad-CBR)
• Biozol Catalog Number: VBL-1283
• Supplier Catalog Number: 1283
• Alternative Catalog Number: VBL-1283
• Manufacturer: Vector Biolabs
• Category: Sonstiges
• Alternative Names: APC Adenovirus

Product Description

Adenomatous polyposis coli gene (APC) is a tumor suppressor gene located on chromosome 5q2. It is inactivated in most colorectal tumors. APC is a cytoplasmic protein that can bind to and promote the degradation of b-catenin. In most colorectal tumors, APC is inactivated. This increases the interaction between b-catenin and Tcf family of transcription factors, leading to increase transcription of genes such as c-Myc. This adenovirus contains APC mini-me fragment. Shih IM., et al., Cancer Res. 2000 Mar 15,60(6):1671-6.

Product Properties

• Concentration: 1x10 10 PFU/ml
• Buffer: DMEM, 2% BSA, 2.5% Glycerol

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