Baculoviral IAP repeat-containing 3 Adenovirus (Ad-BIRC3)

Product Overview

• Article Name: Baculoviral IAP repeat-containing 3 Adenovirus (Ad-BIRC3)
• Biozol Catalog Number: VBL-1446
• Supplier Catalog Number: 1446
• Alternative Catalog Number: VBL-1446
• Manufacturer: Vector Biolabs
• Category: Sonstiges
• Alternative Names: Baculoviral IAP repeat-containing 3 Adenovirus

Product Description

TRAF-interacting proteins include TANK (also designated I-TRAF), ILP, ML-IAP, XAF1, c-IAP and survivin. TANK binds to the conserved TRAF-C domain common to TRAF1, TRAF2 and TRAF3. ML-IAP, c-IAP1 and c-IAP2 are related to the inhibitor of apoptosis protein (IAP) family of Baculovirus proteins. The c-IAPs associate with TRAF1 and TRAF2 through their N-terminal BIR motif-containing domain. IAP-like protein (ILP) also contains an N-terminal BIR motif-containing domain. ILP inhibits activated caspase-3, leading to the resistance of FAS-mediated apoptosis. An additional IAP family member, survivin (also designated TIAP), is expressed in the G2/M phase of the cell cycle and associates with microtubules of the mitotic spindles. Caspase-3 activity increases when a disruption of survivin-microtubule interactions occurs.

Product Properties

• Concentration: 1x10 10 PFU/ml
• Buffer: DMEM, 2% BSA, 2.5% Glycerol

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