Lymphoid enhancer-binding factor 1 Adenovirus (Ad-LEF1)

Product Overview

• Article Name: Lymphoid enhancer-binding factor 1 Adenovirus (Ad-LEF1)
• Biozol Catalog Number: VBL-1457
• Supplier Catalog Number: 1457
• Alternative Catalog Number: VBL-1457
• Manufacturer: Vector Biolabs
• Category: Sonstiges
• Alternative Names: Lymphoid enhancer-binding factor 1 Adenovirus

Product Description

T-cell factor (TCF-1) and lymphoid enhancer-binding factor (for LEF-1, also designated TCF-1(alpha)) compose a family of DNA-binding transcriptional activators that are essential for lymphoid cell development. These transcription factors are activated by the Wnt-1 and Wingless pathways and are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, which mediates DNA binding. LEF-1, TCF-1, and two other family members, TCF-3 and TCF-4, directly bind to cytosolic beta-catenin and facilitate its translocation to the nucleus, where these complexes induce expression of Wnt target genes.

Product Properties

• Concentration: 1x10 10 PFU/ml
• Buffer: DMEM, 2% BSA, 2.5% Glycerol

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