WEE1 homolog Adenovirus (Ad-WEE1)
Catalog Number:
VBL-1459
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| Article Name: | WEE1 homolog Adenovirus (Ad-WEE1) |
| Biozol Catalog Number: | VBL-1459 |
| Supplier Catalog Number: | 1459 |
| Alternative Catalog Number: | VBL-1459 |
| Manufacturer: | Vector Biolabs |
| Category: | Sonstiges |
| Alternative Names: | WEE1 homolog Adenovirus |
| Phosphorylation of Cdc2 on threonine 14 and tyrosine 15 is required to maintain Cdc2 in an inactive state throughout the S and G2 phases of the cell cycle. The human Wee 1 protein, Wee 1 Hu, encodes a tyrosine-specific protein kinase that phosphorylates Cdc2 on tyrosine 15. Myt 1, a member of the Wee 1 family of protein kinases, has been shown to phosphorylate Cdc2 on both threonine 14 and tyrosine 15 in a cyclin-dependent manner. Both Wee 1 Hu and Myt 1 activity are regulated during the cell cycle, suggesting that both proteins play a role in mitotic control. Dephosphorylation of Cdc2 on threonine 14 and tyrosine 15 in late G2 by Cdc25 then activates the Cdc2/cyclin B complex to allow entry into mitosis. |
| Concentration: | 1x10 10 PFU/ml |
| Buffer: | DMEM, 2% BSA, 2.5% Glycerol |
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