Hypoxia-inducible factor 1, alpha subunit inhibitor Adenovirus (Ad-HIF1AN/FIH1)

Catalog Number: VBL-1551
Article Name: Hypoxia-inducible factor 1, alpha subunit inhibitor Adenovirus (Ad-HIF1AN/FIH1)
Biozol Catalog Number: VBL-1551
Supplier Catalog Number: 1551
Alternative Catalog Number: VBL-1551
Manufacturer: Vector Biolabs
Category: Sonstiges
Alternative Names: Hypoxia-inducible factor 1, alpha subunit inhibitor Adenovirus
Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1-alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase and catalyzes the hydroxylation of the beta-carbon of asparagine residue 803 within the C-terminal transactivation domain of HIF-1-alpha. This hyroxylation event blocks the association of HIF-1alpha with coactivators.
Concentration: 1x10 10 PFU/ml
Buffer: DMEM, 2% BSA, 2.5% Glycerol