S-phase kinase-associated protein 2 (p45) Adenovirus (Ad-SKP2)

Product Overview

• Article Name: S-phase kinase-associated protein 2 (p45) Adenovirus (Ad-SKP2)
• Biozol Catalog Number: VEB-1546
• Supplier Catalog Number: 1546
• Alternative Catalog Number: VEB-1546
• Manufacturer: VectorBuilder
• Category: Molekularbiologie
• Alternative Names: S-phase kinase-associated protein 2 (p45) Adenovirus

Product Description

Cyclin A-Cdk2 kinase activity is essential for progression of the cell through S phase. Skp1 p19 and Skp2 p45 are elements of the cyclin A-Cdk2 S phase kinase. The binding of p19 to cyclin A-Cdk2 is p45-dependent, and levels of p45 are substantially increased in transformed cells. Thus, the modulation of Skp2 p45 expression may result in changes in cell cycle control that contribute to the process of cell transformation.

Product Properties

• Buffer: DMEM, 2% BSA, 2.5% Glycerol