Phospholamban Adenovirus (Ad-Phospholamban)
Catalog Number:
VEB-1570
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| Article Name: | Phospholamban Adenovirus (Ad-Phospholamban) |
| Biozol Catalog Number: | VEB-1570 |
| Supplier Catalog Number: | 1570 |
| Alternative Catalog Number: | VEB-1570 |
| Manufacturer: | VectorBuilder |
| Category: | Molekularbiologie |
| Alternative Names: | Phospholamban Adenovirus |
| Phospholamban (PLB, sarco(endo)plasmic-reticulum (SER) regulatory protein) is a 52 amino acid phospho-protein that assembles into a pentamer in the plasma membrane of SER cardiac, smooth and slow-twitch muscle. PLB may regulate cardiac contractility through modulation of SER Ca2+ ATPase (SERCA2a). Nonphosphorylated PLB binds to SERCA2a and inhibits Ca2+ re-uptake into the SER. Phosphorylation of PLB causes dissociation from SERCA2a, allowing Ca2+ uptake into the SER and subsequent ventricular relaxation. |
| Buffer: | DMEM, 2% BSA, 2.5% Glycerol |
