AAV-CReERT2 (AAV serotype 8) AAV (AAV8-CreERT2)

Catalog Number: VEB-7113
Article Name: AAV-CReERT2 (AAV serotype 8) AAV (AAV8-CreERT2)
Biozol Catalog Number: VEB-7113
Supplier Catalog Number: 7113
Alternative Catalog Number: VEB-7113
Manufacturer: VectorBuilder
Category: Molekularbiologie
Alternative Names: AAV-CReERT2 (AAV serotype 8) AAV
A mutated form of estrogen ligand-binding domain (ERT2) that binds to synthetic antagonists (such as tamoxifen or its derivative 4-hydroxy-tamoxifen) but not to circulating estrogens was fused to the Cre recombinase (Cre) to create the CreERT2, which requires the presence of tamoxifen for Cre recombinase activity. Therefore it makes possible to induce the recombination in cells with tamoxifen.This AAV-8 virus expresses CreERT2 under a CMV promoter.
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