Anti-human IgE Antibodies

Antibodies for allergy diagnostics and research

Under the dianova brand we provide a growing selection of premium antibodies available worldwide. This selection includes exceptional primary antibodies for human pathology, as well as an extensive range of secondary antibodies.

Anti-human IgE antibodies for serologic analysis and immunoassay design in allergy diagnostics and research

Immunoglobulin E (IgE) plays an important role in allergic reactions of the immediate type (type I). The total amount of IgE in blood serum is often elevated in allergic diseases such as allergic rhinitis (including especially hay fever and dust mite allergy) or bronchial asthma, but also in food allergies. Increased total IgE titers in serum can also frequently be found in connection with neurodermatitis (atopic eczema).

Clone GHE20 is already established in various immunoassays for the serologic detection of human IgE. Our dianova anti-human IgE (ε) antibody is available for your serologic analyses in allergy research or as a component for immunoassays.

We offer numerous anti-human IgE antibody conjugates for different enzymes and fluorescent dyes. As standard variants you receive unconjugated or conjugated antibodies with AP, HRPO, FITC and Biotin. In addition, we can meet your individual requirements and couple almost any conceivable conjugate to the IgE antibody. Use our conjugation service to customize antibodies for your specific test systems.

Use of anti-human IgE antibodies in ELISA

The mouse clone GHE20 is specific for the epsilon (ε)-chain of human IgE and shows no cross-reaction with human IgG, IgM, or IgA. Our dianova anti-human IgE has been tested in ELISA applications and detects human IgE from various sources (e.g. plasma or serum) with high sensitivity.

Figure 1: Illustration of antibody sensitivity in an ELISA with different concentrations of the anti-human IgE clone GHE20 for detection on IgE-coated analysis plates.

Prod. No.	Product	Conjugation	Qty
DNA-SCR-180656	anti-hu IgE, ms clone GHE20	unconj.	0,1 mg
DNA-SCR-180657	anti-hu IgE, ms clone GHE20	unconj.	0,5 mg
DNA-SCR-180659	anti-hu IgE, ms clone GHE20	HRPO	1 ml
DNA-SCR-180661	anti-hu IgE, ms clone GHE20	FITC	0,5 mg
DNA-SCR-180663	anti-hu IgE, ms clone GHE20	Biotin	0,5 mg
DNA-SCR-180665	anti-hu IgE, ms clone GHE20	Alk. Phos.	1 ml