Stem Cell Research
Modulators from Focus Biomolecules - now 30% off!
Focus Biomolecules 
develops and produces high quality biochemicals for biomedical research. With more than 24 years in the industry, they offer advanced, high quality reagents and a fresh, customer oriented experience.
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FINAL SALE 2026: 30% off all products from Focus Biomolecules. Quote: BIOZOL-FINAL2026 Valid until: December 15, 2026 |
Focus on Stem Cells
Stem cells are unspecialized cells that can renew themselves via cell division and can differentiate to become tissue- or organ-specific cells. Embryonic stem cells are pluripotent – able to develop into any cell type in the human body. Adult or somatic stem cells are typically multipotent cells that are only able to differentiate into cells related to their tissue of origin. Induced pluripotent stem cells are adult stem cells that have been reprogrammed with various transcription factors to enable them to have embryonic stem cell-like properties. Many types of diseases and conditions that would benefit from the generation/regeneration of tissue are being investigated using stem cell-based therapies.
Focus Biomolecules is your go-to source for stem cell culture reagents.
Targeted Modulation of Cellular Signaling Pathways
Small-molecule modulators make it possible to specifically influence key processes in stem cell culture: from generation and reprogramming through proliferation and self-renewal to differentiation. These bioactive molecules can also be used to develop specific culture conditions and defined reagent cocktails.
Focus Biomolecules’ portfolio includes:
Dedifferentiation
Molecules for influencing cellular differentiation states and supporting the return to less specialized states.
Selected Products:
| Art. N° | Product Description | CAS |
|---|---|---|
| FBM-10-2110 | Trichostatin A | HDAC inhibitor | 58880-19-6 |
| FBM-10-3487 | Verteporfin | YAP Inhibitor | 129497-78-5 |
| FBM-10-4622 | Purmorphamine | Smoothened activator | 483367-10-8 |
| FBM-10-4546 | RepSox | TGFß type I / ALK5 inhibitor | 446859-33-2 |
| FBM-10-1287 | SMER28 | Autophagy inducer | 307538-42-7 |
Generation and Reprogramming
Reagents for researching and controlling the reprogramming of cells.
Selected Products:
| Art. N° | Product Description | CAS |
|---|---|---|
| FBM-10-3203 | OAC2 | Enhances stem cell reprogramming | 6019-39-2 |
| FBM-10-4863 | Senexin B | CDK8/19 inhibitor | 1449228-40-3 |
| FBM-10-5666 | WS6 | Stimulates pancreatic ß-cell proliferation | 1421227-53-3 |
| FBM-10-4912 | Chroman 1 | ROCK II inhibitor / Stem cell cytoprotectant | 1273579-40-0 |
Differentiation
Modulators for investigating and specifically influencing the development of stem cells into specialized cell types.
Selected Products:
| Art. N° | Product Description | CAS |
|---|---|---|
| FBM-10-3707 | ITD-1 | TGFß Degrader | 1099644-42-4 |
| FBM-10-3337 | Geranylgeranoic acid | Bioactive Isoprenoid | 35750-48-2 |
| FBM-10-3479 | Compound E | gamma-secretase inhibitor | 209986-17-4 |
| FBM-10-2534 | AM80 | RARα agonist | 94497-51-5 |
| FBM-10-4297 | K-975 | YAP/TAZ-TEAD signaling inhibitor | 2563855-03-6 |
Proliferation
Molecules for researching cell proliferation and the underlying signaling pathways.
Selected Products:
| Art. N° | Product Description | CAS |
|---|---|---|
| FBM-10-4524 | GANT-61 | Hedgehog pathway inhibitor | 500579-04-4 |
| FBM-10-2169 | Prostratin | Promotes neuro-regeneration | 60857-08-1 |
| FBM-10-4295 | TRULI | LATS1/2 kinase inhibitor | 1424635-83-5 |
| FBM-10-4711 | Ezatiostat | GSTP1 inhibitor | 168682-53-9 |
Self-renewal and maintenance
Reagents for investigating stem cell properties and maintaining appropriate cell states.
Selected Products:
| Art. N° | Product Description | CAS |
|---|---|---|
| FBM-10-5468 | Pyrintegrin | ß1-integrin agonist | 1228445-38-2 |
| FBM-10-3945 | TLX agonist 31 | TLX agonist | 3055146-41-0 |
| FBM-10-4048 | CPI203 | BET bromodomain inhibitor | 1446144-04-2 |
| FBM-10-4912 | Chroman 1 | ROCK II inhibitor / Stem cell cytoprotectant | 1446144-04-2 |
| FBM-10-4280 | Emricasan | pan-Caspase inhibitor | 254750-02-2 |
Signal pathway modulation
Molecules for the targeted investigation of relevant signaling pathways, including Hippo and Wnt/β-catenin.
Selected Products for the Hippo Pathway:
| Art. N° | Product Description | CAS |
|---|---|---|
| FBM-10-4297 | K-975 | YAP/TAZ-TEAD signaling inhibitor | 2563855-03-6 |
| FBM-10-4295 | TRULI | LATS1/2 kinase inhibitor | 1424635-83-5 |
| FBM-10-4293 | TM-25659 | TAZ activator | 260553-97-7 |
| FBM-10-4294 | XMU-MP-1 | Potent and selective MST1/2 kinase inhibitor | 2061980-01-4 |
| FBM-10-3924 | PY-60 | YAP Activator | 2765218-56-0 |
Selected Products for the Wnt/β-catenin Pathway:
| Art. N° | Product Description | CAS |
|---|---|---|
| FBM-10-5125 | IM-12 | GSK-3ß inhibitor | 1129669-05-1 |
| FBM-10-5081 | IWR-1 endo | Wnt signaling inhibitor | 1127442-82-3 |
| FBM-10-4605 | Wnt-C59 | Porcupine Inhibitor | 1243243-89-1 |
| FBM-10-1186 | XAV-939 | Tankyrase inhibitor/Cardiomyogenesis inducer | 284028-89-3 |
| FBM-10-1437 | KY-02111 | Wnt pathway inhibitor | 1118807-13-8 |
Other stem cell applications
Selected Products:
| Art. N° | Product Description | CAS |
|---|---|---|
| FBM-10-3049 | BMS-833923 | Smoothened antagonist | 1059734-66-5 |
| FBM-10-5468 | Pyrintegrin | ß1-integrin agonist | 1228445-38-2 |
| FBM-10-3945 | TLX agonist 31 | TLX agonist | 3055146-41-0 |
| FBM-10-4229 | L-755,507 | ß3 adrenergic agonist/CRISPR efficiency enhancer | 159182-43-1 |
| FBM-10-5153 | BML-260 | JSP-1 phosphatase inhibitor | 101439-76-3 |
This may also interest you:
- Cell Culture - Specialized media, supplements and growth factors
- Cell Biology - Matrices for cell maturation and culture
- Human Pluripotent Stem Cells - Differentiation Guide from Qkine
- Neural stem cell research - Growth factors and cytokines from Qkine
13.10.2026