APC Rabbit anti-Mouse CD86 mAb, Monoclonal

Product Overview

• Article Name: APC Rabbit anti-Mouse CD86 mAb, Monoclonal
• Biozol Catalog Number: ABB-A25824
• Supplier Catalog Number: A25824
• Alternative Catalog Number: ABB-A25824-100T,ABB-A25824-5X100T,ABB-A25824-2X100T
• Manufacturer: ABclonal
• Host: Rabbit
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
• Conjugation: APC
• Alternative Names: B7, B70, MB7, B7-2, B7.2, CLS1, Ly58, ETC-1, Ly-58, MB7-2, Cd28l2, TS/A-2, CD86

Product Description

Predicted to enable signaling receptor binding activity. Involved in several processes, including CD40 signaling pathway, activation of phospholipase C activity, and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including cellular response to lipopolysaccharide, defense response to virus, and positive regulation of T cell proliferation. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Is expressed in central nervous system and retina. Used to study Guillain-Barre syndrome. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura, autoimmune disease (multiple), chronic lymphocytic leukemia, chronic obstructive pulmonary disease, and systemic scleroderma. Orthologous to human CD86 (CD86 molecule).

Product Properties

• Clonality: Monoclonal
• Concentration: FC
• Molecular Weight: 35kDa
• NCBI: 12524
• UniProt: P42082
• Purity: Affinity purification
• Target: Cd86

Application Notes

• Application Dilute: FC,5 µl per 10 6 cells in 100 µl volume
• Application Notes: Cross-Reactivity: Mouse. ResearchArea: Immunology Adaptive Immunity T Cells CDImmunology Cell Type Markers CD Non-lineageMicrobiology Interspecies Interaction Host Virus InteractionStem Cells Hematopoietic Progenitors Lymphoid B Lymphocytic LineageStem Cells Hematopoietic Progenitors Myeloid Dendritic Cell LineageStem Cells Hematopoietic Progenitors Myeloid Monocytic LineageImmunology Adaptive Immunity Regulatory T Cells. Shipping: Ice Bag

Images

Flow cytometry:1X10 6 C57BL/6 Mouse Bone Marrow cells (negative control,left) and C57BL/6 Mouse Bone Marrow-Derived M0 Macrophages (right) were surface-stained with ABflo 450 Rabbit anti-Mouse CD11b mAb (A26229,5 µl/Test) and APC Rabbit anti-Mouse CD86 mAb (A25824,5 µl/Test).