Phospho-Bcl-2-S87 Rabbit pAb
Catalog Number:
ABB-AP1071
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| Article Name: | Phospho-Bcl-2-S87 Rabbit pAb |
| Biozol Catalog Number: | ABB-AP1071 |
| Supplier Catalog Number: | AP1071 |
| Alternative Catalog Number: | ABB-AP1071-100UL,ABB-AP1071-20UL,ABB-AP1071-500UL,ABB-AP1071-1000UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Alternative Names: | Bcl-2, PPP1R50, Phospho-Bcl-2-S87 |
| This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. |
| Application Dilute: | WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Rat, ResearchArea: Protein phosphorylation,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Autophagy,Death Receptor Signaling Pathway,Endocrine Metabolism,Mitochondrial metabolism,Mitochondrial markers,Immunology Inflammation,Neuroscience,Neurodegenerative Diseases,Stem Cells. |
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Western blot analysis of lysates from C6 cells, using Phospho-Bcl-2-S87 Rabbit pAb (AP1071) at 1:1000 dilution. C6 cells were treated with Paclitaxel (100 nM) at 37°C for 20 hours. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% BSA. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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