IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.
95 % as determined by Tris-Bis PAGE, 95 % as determined by HPLC.
Target:
IL-17Rc
Application Notes:
Cross-Reactivity: Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles., ResearchArea: Other Recombinant Protein
Recombinant Human IL-17Rc Protein was determined by Tris-Bis PAGE under reducing conditions.
The purity of Human IL-17Rc is greater than 95% as determined by SEC-HPLC.
Immobilized Human IL-17A, His Tag at 1µg/ml (100µl/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC<,sub>,50<,/sub>, of 43.5ng/ml determined by ELISA.
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