Mannose receptor (also known as CD206) is a highly glycosylated type I transmembrane protein that is mainly present on the surface of macrophages, dendritic cells and avascular endothelial cells. CD206 can mediate the internalization of soluble and granular carbohydrate structures, thereby participating in innate immunity. And CD206 binds sulfated and non-sulfated polysaccharide chains through macrophage-mediated endocytosis of glycoproteins. It also acts as a phagocytic receptor for bacteria, fungi and other pathogens or a receptor for dengue virus envelope protein E.
Lyophilized from a 0.22 µm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Application Notes:
Cross-Reactivity: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage,it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA,5% HSA,10% FBS or 5% Trehalose),and aliquot the reconstituted protein solution to minimize free-thaw cycles. ResearchArea: Bio-Markers & CD Antigens
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