ISRE Leeporter(TM) Luciferase Reporter-HEK293 Cell Line Preis auf Anfrage
Biozol Catalog Number:
ABI-14-143ACL
Supplier Catalog Number:
14-143ACL
Alternative Catalog Number:
ABI-14-143ACL-1VIAL
Manufacturer:
Abeomics
Category:
Zellen/Zellkultur
Application:
FA
The ISRE Leeporter(TM) Luciferase Reporter cell line is a stably transfected HEK293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the Interferon-Stimulated Response Element (ISRE). Activation of the reporter cell line triggers phosphorylation of interferon regulatory factors (IRFs). The phosphorylated IRFs can then translocate to the nucleus, bind to ISRE, and lead to the Renilla luciferase reporter protein expression. Functional activity of the cell line has been validated by IFN-alpha (Figure 1).
Application Dilute:
Application: Monitor the JAK/STAT signaling pathway activity. IRF, STING signaling pathway study. Screen for activators or inhibitors of IRF, STING. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glu
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