Polyclonal Antibody to IkB- Alpha (Phospho-Ser32/Ser36), Rabbit

Product Overview

• Article Name: Polyclonal Antibody to IkB- Alpha (Phospho-Ser32/Ser36), Rabbit
• Biozol Catalog Number: ABI-35-1146-50
• Supplier Catalog Number: 35-1146-50
• Alternative Catalog Number: ABI-35-1146-50-50UL
• Manufacturer: Abeomics
• Host: Rabbit
• Category: Antikörper
• Application: IF, IHC, WB
• Species Reactivity: Human, Mouse
• Immunogen: Peptide sequence around phosphorylation site of serine 32/36 (H-D-S(p)-G-L-D-S(p)-M-K) derived from Human IkB-a.
• Alternative Names: I-kappa-B-alpha, IKBA, NF-kappaB inhibitor alpha, NF-KBI, NF-KBIA

Product Description

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.

Product Properties

• Clonality: Polyclonal
• NCBI: 4792
• UniProt: P25963
• Form: Purified
• Target: I?B- Alpha (Phospho-Ser32/Ser36)

Application Notes

• Application Dilute: Predicted MW: 39kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200