HRP conjugated Monoclonal Anti-DM-1&DM-4 Antibody,Mouse IgG1, Multiple

Product Overview

• Article Name: HRP conjugated Monoclonal Anti-DM-1&DM-4 Antibody,Mouse IgG1, Multiple
• Biozol Catalog Number: ABS-DM1-PLY73-200UG
• Supplier Catalog Number: DM1-PLY73-200ug
• Alternative Catalog Number: ABS-DM1-PLY73-200UG
• Manufacturer: AcroBiosystems
• Host: Multiple
• Category: Antikörper
• Species Reactivity: Mouse
• Conjugation: HRP

Product Description

Mertansine (DM1) is a tubulin inhibitor that binds to the ends of microtubules and inhibits microtubule dynamics. DM1(Mertansine) has antitumor activity and functions as a regulator of tubulin. It is an alphaamino acid ester, a carbamate, an epoxide, an organic heterocyclic tetracyclic compound, an organochlorine compound, a mercaptan, and a maydenin alkaloid. DM1, derived from Mydenin, is a cytotoxic component of antibodydrug conjugations that produce antibodydrug conjugations via a sulfhydryl group splice with SPP (nsuccinimide 4 (2pyridyl dithio)) or SMCC (4 (3mercapto2, 5dioxy1 pyrrolidyl) cyclohexanic acid) splice. - Antikörper

Product Properties

• Tag: Mouse IgG1 | Mouse Kappa
• Buffer: PBS, pH7.4
• Form: Powder
• Target: DM-1

Images

Immobilized Trastuzumab-DM1 (T-DM1) at 2 µg/mL (100 µL/well) can bind HRP conjugated Monoclonal Anti-DM-1&DM-4 Antibody,Mouse IgG1 (Cat. No. DM1-PLY73) with a linear range of 0.24-15.63 ng/mL (QC tested).

Immobilized Human Her2, His Tag (Cat. No. HE2-H5225) at 1 µg/mL, add Trastuzumab-DM1 in the 100% Human Serum and then add HRP conjugated Monoclonal Anti-DM-1&DM-4 Antibody,Mouse IgG1 (Cat. No. DM1-PLY73) at 0.5 µg/mL (QC tested).