SARS-CoV-2 Spike Trimer Protein, His Tag (BA.3/Omicron) (MALS verified), Unconjugated, Human

Catalog Number: ABS-SPN-C5225-50UG
Article Name: SARS-CoV-2 Spike Trimer Protein, His Tag (BA.3/Omicron) (MALS verified), Unconjugated, Human
Biozol Catalog Number: ABS-SPN-C5225-50UG
Supplier Catalog Number: SPN-C5225-50ug
Alternative Catalog Number: ABS-SPN-C5225-50UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Virus
Conjugation: Unconjugated
Alternative Names: sars-cov-2
SARSCoV2 Spike Trimer, His Tag (BA.3/Omicron) (SPNC5225) is expressed from human 293 cells (HEK293). It contains AA Val 16 Pro 1213 (Accession QHD43416.1 (A67V,H69del,V70del,T95I,G142D,V143del,Y144del,Y145del,N211del,L212I,G339D,S371F,S373P,S375F,D405N,K417N,N440K,G446S,S477N,T478K,E484A,Q493R,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H,N764K,D796Y,Q954H,N969K,R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P)). The spike mutations are identified on the SARSCoV2 Omicron variant (Pango lineage: BA.3, GISAID clade: GRA, Nextstrain clade: 21M). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the Cterminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARSCoV2 S protein and abolish the furin cleavage site, respectively. - Proteine/Peptide
Molecular Weight: 137.7 kDa
Tag: C-10*His
NCBI: 43416
Buffer: 0.1 M Sodium citrate, pH5.5
Expression System: Val 16 - Pro 1213
Purity: 95%
Form: Powder
Target: Spike protein
SPN-C5225-50ug