MYD88 Antibody, Rabbit, Polyclonal

Product Overview

• Article Name: MYD88 Antibody, Rabbit, Polyclonal
• Biozol Catalog Number: ABT-AP51372
• Supplier Catalog Number: AP51372
• Alternative Catalog Number: ABT-AP51372-100UL
• Manufacturer: Abcepta
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, ICC, WB
• Species Reactivity: Human, Mouse, Rat
• Alternative Names: Myeloid differentiation primary response protein MyD88, MYD88

Product Description

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.

Product Properties

• Clonality: Polyclonal
• NCBI: 4615
• UniProt: Q99836