8-CPT-2Me-cAMP sodium is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium activates Epac1 (EC50 = 2.2 µM), but not PKA (EC50> 10 µM). 8-CPT-2Me-cAMP sodium stimulates Epac-mediated Ca2+ release in pancreatic beta-cells in vitro.
Molecular Weight:
507.82
Purity:
99.0%
CAS Number:
[634207-53-7]
Formula:
C17H16ClN5NaO6PS
* VAT and and shipping costs not included. Errors and price changes excepted
