JNJ-28583113 is a brain-permeable TRPM2 antagonist and blocks phosphorylation of GSK3alpha and beta subunits by inhibiting TRPM2. In addition, JNJ-28583113 inhibits cytokine release from microglia in response to pro-inflammatory stimuli. It has the function of protecting cells from oxidative stress-induced cell death.
Molecular Weight:
366.38
Purity:
>98.0%
CAS Number:
[2765255-93-2]
Formula:
C19H21F3N2O2
Target:
TRP Channel
* VAT and and shipping costs not included. Errors and price changes excepted