Zidesamtinib is a potent, selective, orally active and blood-brain barrier permeable inhibitor of multiple ROS1 fusion and resistance mutations, with IC50 values of 0.7 and 7.9 nM for wild-type ROS1 and ROS1 G2032R, respectively, and does not inhibit TRK.May be useful in studies related to non-small cell lung cancer and other solid tumors.
Molecular Weight:
419.45
Purity:
>99.0%
CAS Number:
[2739829-00-4]
Formula:
C22H22FN7O
Target:
ROS Kinase
* VAT and and shipping costs not included. Errors and price changes excepted
