Rademikibart, CAS [[2648260-80-2]]

Product Overview

• Article Name: Rademikibart, CAS [[2648260-80-2]]
• Biozol Catalog Number: AMO-M54551
• Supplier Catalog Number: M54551
• Alternative Catalog Number: AMO-M54551-1MG,AMO-M54551-5MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: CBP-201

Product Description

Rademikibart is a human IgG4 monoclonal antibody that targets IL-4 Ralpha to block inflammatory signaling induced by IL-4 and IL-13, two important cytokines that drive allergic inflammation, and binds to the human IL-4Ralpha epitope with a KD of 20.7 pM. Rademikibart does not bind to IL-4Ralpha from other species. Rademikibart does not bind to IL-4Ralpha of other species.Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMC, and can be used in studies related to moderate-to-severe Th2 inflammatory diseases.

Product Properties

• CAS Number: [2648260-80-2]
• Target: IL Receptor/Related