Larotrectinib (LOXO-101), CAS [[1223403-58-4]]

Product Overview

• Article Name: Larotrectinib (LOXO-101), CAS [[1223403-58-4]]
• Biozol Catalog Number: AMO-M6151
• Supplier Catalog Number: M6151
• Alternative Catalog Number: AMO-M6151-2MG,AMO-M6151-5MG,AMO-M6151-10MG,AMO-M6151-50MG
• Manufacturer: Abmole Bioscience
• Category: Biochemikalien
• Alternative Names: ARRY-470, larotrectinib

Product Description

Larotrectinib (LOXO-101) is a potent, ATP competitive TRK inhibitor with IC50s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100x selectivity over other kinases, with 2 to 20 nM cellular potency against the TRKA, TRKB, and TRKC kinases.

Product Properties

• Molecular Weight: 428.44
• Purity: 99.56%
• CAS Number: [1223403-58-4]
• Formula: C21H22F2N6O2
• Target: Trk