CCR5 Antibody - middle region
Catalog Number:
ASB-ARP30788_P050
- Images (5)
| Article Name: | CCR5 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP30788_P050 |
| Supplier Catalog Number: | ARP30788_P050 |
| Alternative Catalog Number: | ASB-ARP30788_P050-25UL,ASB-ARP30788_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Human, Porcine |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human CCR5 |
| Alternative Names: | CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5 |
| CCR5 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this protein was also detected in a promyeloblastic cell line, suggesting that CCR5 may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. |
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Host: Rabbit Target Name: CCR5 Sample Tissue: Human HepG2 Whole Cell Antibody Dilution: 1ug/ml |
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Host: Rabbit Target Name: CCR5 Sample Tissue: Human Jurkat Whole Cell Antibody Dilution: 1ug/ml |
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WB Suggested Anti-CCR5 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human heart |
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Host: Rabbit Target Name: CCR5 Sample Type: Human Fetal Liver Antibody Dilution: 1.0ug/ml |
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CCR5 antibody - middle region (ARP30788_P050) in HepG2 Whole Cell using Western Blot |
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