E2F3 Antibody - C-terminal region
Catalog Number:
ASB-ARP38089_P050
- Images (8)
| Article Name: | E2F3 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP38089_P050 |
| Supplier Catalog Number: | ARP38089_P050 |
| Alternative Catalog Number: | ASB-ARP38089_P050-25UL,ASB-ARP38089_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human E2F3 |
| Alternative Names: | E2F-3 |
| E2F3 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. E2F3 binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner. |
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Host: Rabbit Target Name: E2F3 Sample Tissue: Human Lung Tumor Antibody Dilution: 1ug/ml |
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25 ug of the indicated Human whole cell or tissue extracts was loaded onto a 6-18% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. The peptide sequence is also present in isoforms of 42 kDa and 37 kDa. |
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Host: Rabbit Target Name: E2F3 Sample Tissue: Human OVCAR-3 Whole Cell Antibody Dilution: 1ug/ml |
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Host: Rabbit Target Name: E2F3 Sample Tissue: Human Ovary Tumor Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target Name: E2F3 Sample Tissue: Human OVCAR-3 Whole Cell Antibody Dilution: 0.5ug/ml |
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WB Suggested Anti-E2F3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Thymus |
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Host: Mouse Target Name: E2F3 Sample Tissue: Mouse Small Intestine Antibody Dilution: 1ug/ml |
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E2F3 antibody - C-terminal region (ARP38089_P050) in Lung Tumor using Western Blot |
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