NR1I3 Antibody - N-terminal region

Product Overview

• Article Name: NR1I3 Antibody - N-terminal region
• Biozol Catalog Number: ASB-ARP45623_T100
• Supplier Catalog Number: ARP45623_T100
• Alternative Catalog Number: ASB-ARP45623_T100-25UL,ASB-ARP45623_T100-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: IHC, WB
• Species Reactivity: Bovine, Canine, Guinea pig, Human, Mouse, Porcine, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I3
• Alternative Names: CAR, CAR1, MB67

Product Description

NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.

Product Properties

• Clonality: Polyclonal
• Concentration: 1.0 mg/ml
• Molecular Weight: 39kDa
• NCBI: 9970
• UniProt: Q5VTW5
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Images

Human Liver

WB Suggested Anti-NR1I3 Antibody Titration: 1.25ug/ml
Positive Control: Human Liver

Host: Rabbit
Target: NR1I3
Positive control (+): Human liver (LI)
Negative control (-): Human stomach (ST)
Antibody concentration: 5ug/ml

NR1I3 antibody - N-terminal region (ARP45623_T100) in Human Liver using Western Blot