TZ9, Rad6 Ubiquitin Inhibitor, CAS [[1002789-86-7]], Unconjugated
Biozol Catalog Number:
BSS-BS-60286C
Supplier Catalog Number:
bs-60286C
Alternative Catalog Number:
BSS-BS-60286C-10,BSS-BS-60286C-2
Manufacturer:
Bioss
Category:
Biochemikalien
Conjugation:
Unconjugated
TZ9 is a selective and cell permeable inhibitor of human E2 ubiquitin-conjugating enzyme Rad6B. It binds to the Rad6B catalytic site, inhibits Rad6B-induced histone H2A ubiquitination, downregulates intracellular beta-catenin. It can induce G2/M arrest and apoptosis, and inhibit proliferation and migration of metastatic human breast cancer cells (IC50 ~6 µM).
Buffer:
Powder
CAS Number:
[1002789-86-7]
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