IGF-BP-2,also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II, with a much higher binding affinity to IGF-II than IGF-I. IGF-BP-2 has been shown to inhibitand stimulate the growth promoting effects of IGFs, thus serving as a regulator for IGF distribution, function and activity.
Molecular Weight:
6-20 kDa, observed by reducing SDS-PAGE.
Source:
HEK 293
Purity:
> 95% as analyzed by SDS-PAGE.
Form:
Sterile Filtered White lyophilized (freeze-dried) powder.
