Exatecan Mesylate, CAS [[169869-90-3]]

Product Overview

• Article Name: Exatecan Mesylate, CAS [[169869-90-3]]
• Biozol Catalog Number: BYT-ORB1296213
• Supplier Catalog Number: orb1296213
• Alternative Catalog Number: BYT-ORB1296213-10, BYT-ORB1296213-100, BYT-ORB1296213-25, BYT-ORB1296213-50, BYT-ORB1296213-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: DX8951f, ADC Cytotoxin, ADCCytotoxin, Exatecan, Exatecan Mesylate, Inhibitor, inhibit, Topoisomerase, Topo I

Product Description

Exatecan Mesylate (DX-8951f) is a potent inhibitor of DNA topoisomerase I, exhibiting an IC50 of 2.2 µM. This camptothecin analog has demonstrated antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft models, supporting its research use in oncology and cancer pharmacology.

Product Properties

• Molecular Weight: 531.55
• Purity: 99.90% (May vary between batches)
• CAS Number: [169869-90-3]
• Formula: C25H26FN3O7S
• Target: Topoisomerase,ADC Cytotoxin

Application Notes

• Application Notes: Solubility: H2O:6 mg/mL (11.29 mM),DMSO:8 mg/mL (15.05 mM)