Ningetinib Tosylate, CAS [[1394820-77-9]]

Product Overview

• Article Name: Ningetinib Tosylate, CAS [[1394820-77-9]]
• Biozol Catalog Number: BYT-ORB1296250
• Supplier Catalog Number: orb1296250
• Alternative Catalog Number: BYT-ORB1296250-1, BYT-ORB1296250-10, BYT-ORB1296250-100, BYT-ORB1296250-25, BYT-ORB1296250-5, BYT-ORB1296250-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: cMet, c-Met, cMet/HGFR, c-Met/HGFR, AXL, Axl, HGFR, Mer, inhibit, Inhibitor, Ningetinib, Ningetinib Tosylate, TAM Receptor, TAMReceptor, Vascular endothelial growth factor receptor, VEGFR, VEGFR2, Tyro3

Product Description

Ningetinib Tosylate is a potent, orally active small molecule inhibitor targeting Axl, VEGFR2, and c-Met kinases with IC50 values below 10 nM. It is utilized in preclinical cancer research, particularly in studies involving tumor angiogenesis, metastasis, and resistance mechanisms in both cellular and animal models.

Product Properties

• Molecular Weight: 728.79
• Purity: 99.93% (May vary between batches)
• CAS Number: [1394820-77-9]
• Formula: C38H37FN4O8S
• Target: c-Met/HGFR,VEGFR,TAM Receptor

Application Notes

• Application Notes: Solubility: DMSO:8 mg/mL (10.98 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.37 mM)