STING agonist-12, CAS [[2259624-71-8]]

Product Overview

• Article Name: STING agonist-12, CAS [[2259624-71-8]]
• Biozol Catalog Number: BYT-ORB1297845
• Supplier Catalog Number: orb1297845
• Alternative Catalog Number: BYT-ORB1297845-1, BYT-ORB1297845-1, BYT-ORB1297845-10, BYT-ORB1297845-100, BYT-ORB1297845-200, BYT-ORB1297845-25, BYT-ORB1297845-5, BYT-ORB1297845-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Inhibitor, MPYS, inhibit, MITA, ERIS, HEK293T, TMEM173, Stimulator of Interferon Genes, STING, STING activator Compound 53, STING agonist 12, STING agonist12, STING agonist-12

Product Description

Compound 53, an oxindole-based STING agonist, potently activates human STING with an EC50 of 185 nM in both primary and immortalized cells, eliciting a characteristic cytokine profile. This small molecule is a valuable tool for probing STING pathway immunobiology in vitro and has been utilized in preclinical in vivo studies for cancer immunotherapy research.

Product Properties

• Molecular Weight: 490.88
• Purity: 98.29% (May vary between batches)
• CAS Number: [2259624-71-8]
• Formula: C25H19ClF4N2O2
• Target: STING

Application Notes

• Application Notes: Solubility: DMSO:60 mg/mL (122.23 mM)