GSK778 hydrochloride is a potent and selective BD1 bromodomain inhibitor of BET proteins, demonstrating low nanomolar IC50 values. It mimics pan-BET inhibitor effects in cancer models, making it a valuable tool for epigenetic research in oncology, applicable in both cellular and in vivo studies of transcriptional regulation and tumor progression.
Molecular Weight:
548.08
Purity:
98.35% (May vary between batches)
CAS Number:
[2863657-79-6]
Formula:
C30H34ClN5O3
Target:
Apoptosis,Epigenetic Reader Domain
Application Notes:
Solubility: DMSO:50 mg/mL (91.23 mM)
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