GSK3685032, CAS [[2170137-61-6]]

Product Overview

• Article Name: GSK3685032, CAS [[2170137-61-6]]
• Biozol Catalog Number: BYT-ORB1298013
• Supplier Catalog Number: orb1298013
• Alternative Catalog Number: BYT-ORB1298013-1, BYT-ORB1298013-1, BYT-ORB1298013-10, BYT-ORB1298013-100, BYT-ORB1298013-2, BYT-ORB1298013-200, BYT-ORB1298013-25, BYT-ORB1298013-5, BYT-ORB1298013-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: cancer, DNA Methyltransferase, DNA MTases, DNAMethyltransferase, DNMT1, DNMTs, GSK3685032, GSK-3685032, GSK 3685032, leukemia, GDM-1, lymphoma, Inhibitor, inhibit, multiple myeloma, MV4-11

Product Description

GSK3685032 is a potent, selective, and reversible non-covalent inhibitor of DNMT1 (IC50 = 36 nM). It induces DNA demethylation and gene reactivation, demonstrating robust anti-proliferative effects in cancer cell lines and in vivo tumor models, making it a valuable tool for epigenetic and oncology research.

Product Properties

• Molecular Weight: 420.53
• Purity: 99.49% (May vary between batches)
• CAS Number: [2170137-61-6]
• Formula: C22H24N6OS
• Target: DNA Methyltransferase

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.76 mM),DMSO:26.4 mg/mL (62.78 mM)