BC-LI-0186, CAS [[695207-56-8]]

Product Overview

• Article Name: BC-LI-0186, CAS [[695207-56-8]]
• Biozol Catalog Number: BYT-ORB1298035
• Supplier Catalog Number: orb1298035
• Alternative Catalog Number: BYT-ORB1298035-1, BYT-ORB1298035-1, BYT-ORB1298035-10, BYT-ORB1298035-100, BYT-ORB1298035-2, BYT-ORB1298035-25, BYT-ORB1298035-5, BYT-ORB1298035-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Inhibitor, leucyl-tRNA synthetase, Leucyl-tRNA synthetase, H460, lung cancer, KRAS G12D, inhibit, A549, 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide, BC LI 0186, BC-LI 0186, BCLI0186, BC-LI0186, BC-LI-0186, Aminoacyl-tRNA Synthetase, RagD, rapamycin-resistant, Ras-related GTP-binding protein D (RagD), tRNA Synthetase, aaRS

Product Description

BC-LI-0186 is a potent, selective inhibitor of the LRS-RagD interaction with a Kd of 42.1 nM. It suppresses mTORC1 signaling by this mechanism, inhibiting the growth of rapamycin-resistant cancer cells in vitro, and is applied in lung cancer research.

Product Properties

• Molecular Weight: 429.53
• Purity: 99.71% (May vary between batches)
• CAS Number: [695207-56-8]
• Formula: C22H27N3O4S
• Target: Others

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.31 mM),DMSO:100 mg/mL (232.81 mM)