HPK1-IN-7, CAS [[2320462-65-3]]

Product Overview

• Article Name: HPK1-IN-7, CAS [[2320462-65-3]]
• Biozol Catalog Number: BYT-ORB1298074
• Supplier Catalog Number: orb1298074
• Alternative Catalog Number: BYT-ORB1298074-1, BYT-ORB1298074-1, BYT-ORB1298074-10, BYT-ORB1298074-100, BYT-ORB1298074-200, BYT-ORB1298074-25, BYT-ORB1298074-5, BYT-ORB1298074-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: MAP4K, MAPK Kinase Kinase Kinase, MC38, HPK1 IN 7, HPK1IN7, HPK-1-IN-7, HPK1-IN-7, inhibit, Inhibitor, oral, model, PD1, selectivity, tumor

Product Description

HPK1-IN-7 is an orally bioavailable, small molecule inhibitor of Hematopoietic Progenitor Kinase 1. It demonstrates selectivity over related kinases IRAK4 (IC50 = 59 nM) and GLK (IC50 = 140 nM). This compound is a valuable research tool for investigating HPK1 function in immune cell signaling and for preclinical studies in immuno-oncology.

Product Properties

• Molecular Weight: 458.47
• Purity: 99.79% (May vary between batches)
• CAS Number: [2320462-65-3]
• Formula: C24H22N6O4
• Target: MAPK

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.72 mM),DMSO:125 mg/mL (272.65 mM)