SHR0302, CAS [[1445987-21-2]]

Product Overview

• Article Name: SHR0302, CAS [[1445987-21-2]]
• Biozol Catalog Number: BYT-ORB1298293
• Supplier Catalog Number: orb1298293
• Alternative Catalog Number: BYT-ORB1298293-1, BYT-ORB1298293-1, BYT-ORB1298293-10, BYT-ORB1298293-100, BYT-ORB1298293-25, BYT-ORB1298293-5, BYT-ORB1298293-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: collagen, B-cell, arthritis, ARQ252, ARQ-252, ARQ 252, anti-inflammatory, anti-proliferation, Apoptosis, Inhibitor, Janus kinase, JAK1, JAK1-STAT3, JAK, inhibit, migration, fibrosis, hepatic, SHR 0302, SHR0302, SHR-0302, phosphorylation, Th17

Product Description

SHR0302 (ARQ252) is a selective JAK1 inhibitor, demonstrating >10-fold selectivity over JAK2, 77-fold over JAK3, and 420-fold over Tyk2. This small molecule is a valuable research tool for investigating JAK1-dependent pathways in both cellular and animal models of autoimmune and inflammatory diseases.

Product Properties

• Molecular Weight: 414.48
• Purity: 99.11% (May vary between batches)
• CAS Number: [1445987-21-2]
• Formula: C18H22N8O2S
• Target: Apoptosis,JAK

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.83 mM),DMSO:30 mg/mL (72.38 mM)