DS-1205, CAS [[1855860-24-0]]

Product Overview

• Article Name: DS-1205, CAS [[1855860-24-0]]
• Biozol Catalog Number: BYT-ORB1298349
• Supplier Catalog Number: orb1298349
• Alternative Catalog Number: BYT-ORB1298349-1, BYT-ORB1298349-1, BYT-ORB1298349-10, BYT-ORB1298349-25, BYT-ORB1298349-5
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: c-Met/HGFR, DS 1205, DS1205, DS-1205, DS-1205b, AXL, Axl, Inhibitor, Mer, NIH3T3, MET, migration, kinase, inhibit, Tropomyosin related kinase receptor, TRKA, Trk Receptor, Tyro3, tumor, TAM Receptor, TAMReceptor

Product Description

DS-1205 is a highly potent and selective AXL kinase inhibitor (IC50 = 1.3 nM), with additional activity against MER, MET, and TRKA kinases. This small molecule has demonstrated efficacy in suppressing cell migration in vitro and impeding tumor growth in animal models, supporting its research use in oncology and metastasis studies.

Product Properties

• Molecular Weight: 735.8
• Purity: 99.75% (May vary between batches)
• CAS Number: [1855860-24-0]
• Formula: C41H42FN5O7
• Target: TAM Receptor,Trk receptor,c-Met/HGFR

Application Notes

• Application Notes: Solubility: DMSO:45 mg/mL (61.16 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.72 mM)