BMS-911543, CAS [[1271022-90-2]]
Catalog Number:
BYT-ORB1300463
Product Overview
Article Name:
BMS-911543, CAS [[1271022-90-2]]
Biozol Catalog Number:
BYT-ORB1300463
Supplier Catalog Number:
orb1300463
Alternative Catalog Number:
BYT-ORB1300463-1, BYT-ORB1300463-1, BYT-ORB1300463-5, BYT-ORB1300463-10, BYT-ORB1300463-25, BYT-ORB1300463-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
SET-2, Tyrosine Kinases, TyrosineKinases, TYK2, BMS 911543, BMS911543, BMS-911543, Inhibitor, HistoneMethyltransferase, Histone Methyltransferase, JAK3, Janus kinase, JAK2, JAK, JAK1, inhibit
Product Description
BMS-911543 is a highly selective JAK2 inhibitor (IC50 = 1.1 nM) with significant selectivity over JAK1, JAK3, and TYK2. It is a valuable research tool for investigating JAK2-dependent pathways in myeloproliferative neoplasms and hematological malignancies, as evidenced in both in vitro and in vivo preclinical studies.
Product Properties
Molecular Weight:
432.52
Purity:
99.98% (May vary between batches)
CAS Number:
[1271022-90-2]
Formula:
C23H28N8O
Target:
Histone Methyltransferase,Tyrosine Kinases,JAK
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.62 mM),DMSO:34 mg/mL (78.61 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),Ethanol:21 mg/mL (48.55 mM)