Thioperamide maleate (MR-12842 maleate) is a potent and selective histamine H3 receptor antagonist, with a Ki of 4.3 nM for receptor binding and 31 nM for inhibiting [H]histamine synthesis. This compound is widely used in neuroscience research to study H3 receptor function in both in vitro and in vivo models of sleep, cognition, and energy homeostasis.
Molecular Weight:
408.52
Purity:
99.88% (May vary between batches)
CAS Number:
[148440-81-7]
Formula:
C19H28N4O4S
Target:
Histamine Receptor
Application Notes:
Solubility: DMSO:55 mg/mL (134.63 mM)
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